N-DBCO-N-bis(PEG2-C2-NHS ester)
Product Specifications
UNSPSC Description
N-DBCO-N-bis(PEG2-C2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-DBCO-N-bis(PEG2-C2-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-dbco-n-bis-peg2-c2-nhs-ester.html
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(N(CCOCCOCCC(ON(C4=O)C(CC4)=O)=O)CCOCCOCCC(ON(C5=O)C(CC5)=O)=O)=O
Molecular Weight
818.82
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140585/N-DBCO-N-bis-PEG2-C2-NHS-ester-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140585/N-DBCO-N-bis-PEG2-C2-NHS-ester-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2128735-29-3
Available Sizes
Curated Selection
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