Sabcomeline (hydrochloride)
Sabcomeline (SB-202026) hydrochloride is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline hydrochloride can be used for Alzheimer's disease research[1][2].
Product Specifications
CAS Number
159912-58-0
Product Name Alternative
SB-202026 (hydrochloride) ; Memric (hydrochloride)
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sabcomeline-hydrochloride.html
Purity
99.81
Solubility
H2O : 125 mg/mL (ultrasonic)
Smiles
CO/N=C([C@@H]1C2CCN(CC2)C1)\C#N.Cl
Molecular Formula
C10H16ClN3O
Molecular Weight
229.71
References & Citations
[1]Hosoi R, Kobayashi K, Ishida J, Yamaguchi M, Inoue O. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain. Ann Nucl Med. 2003;17 (2) :123-130. |[2]Hatcher JP, Loudon JM, Hagan JJ, Clark MS. Sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, reverses delay-induced deficits in the T-maze. Psychopharmacology (Berl) . 1998;138 (3-4) :275-282.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAChR1
Available Sizes
Frequently Asked Questions
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