Sabcomeline (hydrochloride)

Sabcomeline (SB-202026) hydrochloride is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline hydrochloride can be used for Alzheimer's disease research[1][2].

Product Specifications

CAS Number

[159912-58-0]

Product Name Alternative

SB-202026 (hydrochloride) ; Memric (hydrochloride)

UNSPSC

12352005

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sabcomeline-hydrochloride.html

Purity

99.81

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

CO/N=C([C@@H]1C2CCN(CC2)C1)\C#N.Cl

Molecular Formula

C10H16ClN3O

Molecular Weight

229.71

References & Citations

[1]Hosoi R, Kobayashi K, Ishida J, Yamaguchi M, Inoue O. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain. Ann Nucl Med. 2003;17 (2) :123-130. |[2]Hatcher JP, Loudon JM, Hagan JJ, Clark MS. Sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, reverses delay-induced deficits in the T-maze. Psychopharmacology (Berl) . 1998;138 (3-4) :275-282.