Cis-Epoxysuccinic acid
Cis-Epoxysuccinic acid is a succinate receptor (SUCNR1/GPR91) agonist. cis-Epoxysuccinic acid inhibits cAMP levels with an EC50 value of 2.7 μM. cis-Epoxysuccinic acid can be used for the research of cardiovascular system[1].
Product Specifications
CAS Number
[16533-72-5]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Succinate Receptor 1
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cis-epoxysuccinic-acid.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C([C@@H]1O[C@@H]1C(O)=O)O
Molecular Formula
C4H4O5
Molecular Weight
132.07
Precautions
H315, H319
References & Citations
[1]Geubelle P, et al. Identification and pharmacological characterization of succinate receptor agonists. Br J Pharmacol. 2017 May;174 (9) :796-808.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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