GSK-3β inhibitor 11
Product Specifications
UNSPSC Description
GSK-3β inhibitor 11 (compound 21) is a glycogen synthase kinase-3β (GSK-3β) inhibitor (IC50=10.02 μM). GSK-3β inhibitor 11 can be used in neurodegenerative disease research[1].
Target Antigen
GSK-3
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR;Stem Cell/Wnt
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gsk-3β-inhibitor-11.html
Solubility
DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C1C2=C(C(N1CC(NC3=NC(C4=CC(OC)=CC=C4)=CS3)=O)=O)C=CC=C2
Molecular Weight
393.42
References & Citations
[1]Fu G, et al. Pharmacophore Modeling, Ensemble Docking, Virtual Screening, and Biological Evaluation on Glycogen Synthase Kinase-3β. Mol Inform. 2014 Sep;33(9):610-26.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148132/GSK-3β-inhibitor-11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148132/GSK-3β-inhibitor-11-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
536731-65-4
Available Sizes
Curated Selection
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