Oxidized low density lipoprotein (Human)
Product Specifications
UNSPSC Description
Oxidized low density lipoprotein (Human) (Human ox-LDL) is involved in atherogenesis. Oxidized low density lipoprotein (Human) induces endothelial dysfunction via cytoplasmic adapter protein TRAF3IP2. Oxidized low density lipoprotein (Human) can stimulate the activation of endothelial cells and the production of adhesion molecules, and inhibits eNOS activity and NO production. Oxidized low density lipoprotein (Human) can activate NLRP3 inflammasome in macrophages[1].
Target Antigen
NO Synthase; NOD-like Receptor (NLR)
Type
Biochemical Assay Reagents
Related Pathways
Immunology/Inflammation
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/oxidized-low-density-lipoprotein-human.html
Smiles
[Oxidizedlowdensitylipoprotein(Human)]
References & Citations
[1]Poznyak AV, et al. Overview of OxLDL and Its Impact on Cardiovascular Health: Focus on Atherosclerosis. Front Pharmacol. 2021 Jan 11;11:613780.
Shipping Conditions
Isolate blue ice and the product with bubble pack to avoid direct contact
Storage Conditions
Store at 4°C, do not freeze
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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