Chinese gallotannin

Chinese gallotannin is a non-specific promiscuous α-amylase inhibitor with a Ki of 0.82 μg/mL for human salivary α-amylase. Chinese gallotannin can be used for the research of diabetes[1].

Product Specifications

CAS Number

[5424-20-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Amylases

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/chinese-gallotannin.html

Concentration

10mM

Purity

96.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(OC(C2=CC(O)=C(C(O)=C2)O)=O)=C(C(O)=C1)O)O[C@@H]3[C@H]([C@@H](O[C@@H]([C@H]3OC(C4=CC(OC(C5=CC(O)=C(C(O)=C5)O)=O)=C(C(O)=C4)O)=O)COC(C6=CC(OC(C7=CC(O)=C(C(O)=C7)O)=O)=C(C(O)=C6)O)=O)OC(C8=CC(OC(C9=CC(O)=C(C(O)=C9)O)=O)=C(C(O)=C8)O)=O)OC(C%10=CC(OC(C%11=CC(O)=C(C(O)=C%11)O)=O)=C(C(O)=C%10)O)=O

Molecular Formula

C76H52O46

Molecular Weight

1701.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Szabó K, et al. Gallotannins are non-specific inhibitors of α-amylase: Aggregates are the active species taking part in inhibition. Chem Biol Drug Des. 2021 Feb;97 (2) :349-357.