FR168888
FR168888 is an inhibitor of Na+/H+ exchange with a Ki value of 6.4 nM[1].
Product Specifications
CAS Number
168620-46-0
UNSPSC
12352005
Target
Na+/H+ Exchanger (NHE)
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/fr168888.html
Smiles
O=C(NC(N)=N)C1=CC(N2C=CC=C2)=CC(CO)=C1.CS(=O)(O)=O
Molecular Formula
C14H18N4O5S
Molecular Weight
354.38
References & Citations
[1]F Ohara, et al. Protective effect of FR168888, a new Na+/H+ exchange inhibitor, on ischemia and reperfusion-induced arrhythmia and myocardial infarction in rats: in comparison with other cardioprotective compounds. Jpn J Pharmacol. 1999 Aug;80 (4) :295-302.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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