Baicalein
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor with an IC50 value of 3.12 μM.
Product Specifications
CAS Number
491-67-8
Product Name Alternative
5,6,7-Trihydroxyflavone
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ferroptosis; Influenza Virus; Xanthine Oxidase
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Baicalein.html
Purity
99.13
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=CC=C2)OC3=CC(O)=C(O)C(O)=C13
Molecular Formula
C15H10O5
Molecular Weight
270.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Shieh DE, et al. Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin. Anticancer Res. 2000 Sep-Oct;20 (5A) :2861-5.|[2]Patwardhan RS, et al. Baicalein exhibits anti-inflammatory effects via inhibition of NF-κB transactivation. Biochem Pharmacol. 2016 May 15;108:75-89.|[3]Ma X, et al. Baicalein suppresses metastasis of breast cancer cells by inhibiting EMT via downregulation of SATB1 and Wnt/β-catenin pathway.
 Drug Des Devel Ther. 2016 Apr 18;10:1419-41.|[4]Kong EK, et al. A novel anti-fibrotic agent, baicalein, for the treatment of myocardial fibrosis in spontaneously hypertensiverats. Eur J Pharmacol. 2011 May 11;658 (2-3) :175-81.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
Launched
Available Sizes
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