E3 ligase Ligand 44
E3 ligase Ligand 44 is a ligand for E3 ligase, used for the synthesis of PROTAC AR Degrader-7 (HY-160221) [1].
Product Specifications
CAS Number
[2505504-49-2]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-44.html
Smiles
O=C[C@@H]1[C@]2([H])[C@@]1([H])CN(C3=C(F)C=C(C(N(C4C(NC(CC4)=O)=O)C5=O)=O)C5=C3)C2
Molecular Formula
C19H16FN3O5
Molecular Weight
385.35
References & Citations
[1]DU wu, et al. Dual-function chimeric heterocyclic compound for targeted degradation of androgen receptor and application thereof. CN111825657A. 2020.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
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