ERK2 IN-5
ERK2 IN-5 (Compound 5g) is an inhibitor for ERK2, and exhibits good affinity to ERK2 and JNK3 with Ki of 86 and 550 nM[1].
Product Specifications
CAS Number
[353250-09-6]
UNSPSC
12352101
Target
ERK; JNK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/erk2-in-5.html
Smiles
O=C(C1=CC(C2=NNC=C2C3=CC=CC(Cl)=C3)=CN1)NCC4=CC=CC=C4
Molecular Formula
C21H17ClN4O
Molecular Weight
376.84
References & Citations
[1]Aronov AM, et al., Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors. J Med Chem. 2007 Mar 22;50 (6) :1280-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERK2; JNK3
Curated Selection
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