Kukoamine A
Product Specifications
UNSPSC Description
Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (Ki, 1.8 μM), with antihypertensive activity[1].
Target Antigen
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/kukoamine-a.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)|H2O : 125 mg/mL (ultrasonic)
Smiles
O=C(NCCCNCCCCNCCCNC(CCC1=CC=C(O)C(O)=C1)=O)CCC2=CC=C(O)C(O)=C2
Molecular Weight
530.66
References & Citations
[1]Ponasik JA, et al. Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase. Biochem J. 1995 Oct 15;311 ( Pt 2):371-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N2392/Kukoamine-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N2392/Kukoamine-A-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
75288-96-9
Available Sizes
Curated Selection
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