What is the catalog number for Ataluren?

The catalog number for Ataluren is HY-14832.

What sizes are available for Ataluren?

Ataluren is available in the following size(s): 5 mg, 10 mg, 10 mM - 1 mL, 50 mg, 100 mg, 200 mg.

How many pack sizes does Ataluren come in?

Ataluren is available in 6 different pack sizes.

Is Ataluren in stock?

Ataluren is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ataluren?

Ataluren is manufactured by QuantiMol.

What is the estimated delivery time for Ataluren?

Estimated delivery time for Ataluren is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ataluren?

The safety data sheet for Ataluren is available here: http://file.medchemexpress.com/batch_PDF/HY-14832/Ataluren-SDS-MedChemExpress.pdf.

Ataluren

Ataluren (PTC124) is an orally available CFTR-G542X nonsense allele inhibitor.

Product Specifications

CAS Number

775304-57-9

Product Name Alternative

PTC124

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Autophagy; CFTR

Type

Reference compound

Related Pathways

Autophagy; Membrane Transporter/Ion Channel

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/PTC124.html

Purity

99.62

Solubility

DMSO : ≥ 52 mg/mL

Smiles

O=C(C1=CC=CC(C2=NOC(C3=CC=CC=C3F)=N2)=C1)O

Molecular Formula

C15H9FN2O3

Molecular Weight

284.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Pettit RS, et al. CFTR Modulators for the Treatment of Cystic Fibrosis. P T. 2014 Jul;39 (7) :500-11.|[2]Welch EM, et al. PTC124 targets genetic disorders caused by nonsense mutations. Nature, 2007, 447 (7140), 87-91.|[3]Miller JN, et al. The novel Cln1 (R151X) mouse model of infantile neuronal ceroid lipofuscinosis (INCL) for testing nonsense suppression therapy. Hum Mol Genet. 2015 Jan 1;24 (1) :185-96.