TCS JNK 5a
Product Specifications
UNSPSC Description
TCS JNK 5a is a potent JNK3 inhibitor with a pIC50 of 6.7. TCS JNK 5a also inhibits JNK2 with a pIC50 of 6.5.
Target Antigen
Apoptosis; JNK
Type
Reference compound
Related Pathways
Apoptosis;MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/TCS-JNK-5a.html
Solubility
DMSO : 20 mg/mL (ultrasonic)
Smiles
O=C(C1=C2C=CC=CC2=CC=C1)NC3=C(C#N)C(CCCC4)=C4S3
Molecular Weight
332.42
References & Citations
[1]Angell RM, et al. N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1296-301.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15881/TCS-JNK-5a-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15881/TCS-JNK-5a-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
312917-14-9
Available Sizes
Curated Selection
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