(-) -Eleutherin
(-) -Eleutherin is a pyranonaphthoquinone derivative that exhibits cytotoxic activity by inhibiting DNA topoisomerase II. (-) -Eleutherin has been shown to have promising potential as a medicinal compound due to its association with naphthoquinones. (-) -Eleutherin demonstrates significant DNA fragmentation rates, indicating its strong cytotoxic effects on cells. Additionally, (-) -Eleutherin possesses higher antioxidant potential compared to control samples, contributing to its therapeutic efficacy.
Product Specifications
CAS Number
22768-95-2
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/minus-eleutherin.html
Smiles
O=C1C2=C(OC)C=CC=C2C(C3=C1[C@@H](O[C@@H](C3)C)C)=O
Molecular Formula
C16H16O4
Molecular Weight
272.30
References & Citations
[1]Toxicity evaluation of Eleutherine plicata Herb. extracts and possible cell death mechanism
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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