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(S) -Mapracorat

(S) -Mapracorat is a selective and less active glucocorticoid receptor agonist.

Product Specifications

CAS Number

887375-15-7

Product Name Alternative

(S) -ZK-245186; (S) -BOL-303242X

UNSPSC

12352005

Target

Glucocorticoid Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/_S_-Mapracorat.html

Purity

99.85

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC(C)(C1=C(OCC2)C2=CC(F)=C1)C[C@](O)(CNC3=C4C=CC(C)=NC4=CC=C3)C(F)(F)F

Molecular Formula

C25H26F4N2O2

Molecular Weight

462.48

References & Citations

[1]Bäumer W , et al. The selective glucocorticoid receptor agonist mapracorat displays a favourable safety-efficacy ratio for the topical treatment of inflammatory skin diseases in dogs. Vet Dermatol. 2017 Feb; 28 (1) :46-e11.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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