Guattegaumerine

Guattegaumerine is a bisbenzylisoquinoline alkaloid with antimitotic, cytotoxic and neuroprotective activities[1].

Product Specifications

CAS Number

[21446-35-5]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/guattegaumerine.html

Solubility

10 mM in DMSO

Smiles

COC(C=C(CCN1C)C([C@H]1CC2=CC(OC3=CC=C(C=C3)C[C@@H]4C5=CC(O)=C(OC)C=C5CCN4C)=C(C=C2)O)=C6)=C6O

Molecular Formula

C36H40N2O6

Molecular Weight

596.71

References & Citations

[1]Qing Lü, et al. Guattegaumerine protects primary cultured cortical neurons against oxidative stress injury induced by hydrogen peroxide concomitant with serum deprivation. Cell Mol Neurobiol. 2009 May;29 (3) :355-64.|[2]J Leclercq, et al. Antimitotic and cytotoxic activities of guattegaumerine, a bisbenzylisoquinoline alkaloid. Planta Med