SETD7, Human (His)

The SETD7 protein is a histone methyltransferase that specifically monomethylates H3K4, a mark associated with transcriptional activation. Its role in gene activation extends to the collagenase and insulin genes, specifically at the insulin promoter when IPF1/PDX-1 is recruited. SETD7 Protein, Human (His) is the recombinant human-derived SETD7 protein, expressed by E. coli , with N-His labeled tag. The total length of SETD7 Protein, Human (His) is 365 a.a., with molecular weight of 47-50 kDa.

DSDDEMVE EAVEGHLDDD GLPHGFCTVT YSSTDRFEGN FVHGEKNGRG KFFFFDGSTL EGYYVDDALQ GQGVYTYEDG GVLQGTYVDG ELNGPAQEYD TDGRLIFKGQ YKDNIRHGVC WIYYPDGGSL VGEVNEDGEM TGEKIAYVYP DERTALYGKF IDGEMIEGKL ATLMSTEEGR PHFELMPGNS VYHFDKSTSS CISTNALLPD PYESERVYVA ESLISSAGEG LFSKVAVGPN TVMSFYNGVR ITHQEVDSRD WALNGNTLSL DEETVIDVPE PYNHVSKYCA SLGHKANHSF TPNCIYDMFV HPRFGPIKCI RTLRAVEADE ELTVAYGYDH SPPGKSGPEA PEWYQVELKA FQATQQK