T-2 Toxin-13C24

T-2 Toxin-13C24 (T-2 Mycotoxin-13C24) is 13C-labeled T-2 Toxin (HY-N6792). T-2 Toxin (T-2 Mycotoxin) is a toxic trichothecene mycotoxin produced by various Fusarium species in feedstuffs and cereal grains. T-2 Toxin (T-2 Mycotoxin) inhibits the synthesis of DNA and RNA, interferes with the metabolism of membrane phospholipids, and increases the level of liver lipid peroxides. T-2 Toxin (T-2 Mycotoxin) induces apoptosis in the immune system, gastrointestinal tissues, and fetal tissues[1][2][3].

[13CH3][13C@]12[13C]3([13C@@]([H])([13C@@H]([13C@H]2O[13C]([13CH3])=O)O)O[13C@]4([13C@]1([13CH2]O[13C]([13CH3])=O)[13CH2][13C@@H]([13C]([13CH3])=[13CH]4)O[13C]([13CH2][13CH]([13CH3])[13CH3])=O)[H])O[13CH2]3

[1]Li Y, et al. T-2 toxin, a trichothecene mycotoxin: review of toxicity, metabolism, and analytical methods. J Agric Food Chem. 2011 Apr 27;59(8):3441-53.|[2]Sun YX, et al. Toxicokinetics of T-2 toxin and its major metabolites in broiler chickens after intravenous and oral administration. J Vet Pharmacol Ther. 2015 Feb;38(1):80-5|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220.