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Utrophin activator-1

Utrophin activator-1 (compound 3) is an utrophin upregulator with an EC50 of 1.8 μM. Utrophin activator-1 can be used for Duchenne muscular dystrophy research[1].

Product Specifications

CAS Number

[381208-40-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/utrophin-activator-1.html

Solubility

10 mM in DMSO

Smiles

CCN(CC)C1=CC=C(C=C1)N2N=C3C=C(C)C(=CC3=N2)N

Molecular Formula

C17H21N5

Molecular Weight

295.38

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Daniel R Chancellor, et al. Discovery of 2-arylbenzoxazoles as upregulators of utrophin production for the treatment of Duchenne muscular dystrophy. J Med Chem. 2011 May 12;54 (9) :3241-50.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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