TGF-beta/Smad Antibody

Anti-ACVR2B Antibody is a highly specific monoclonal antibody targeting the human activin receptor type IIB (ACVR2B) . The compound binds to the extracellular domain of ACVR2B to effectively block signaling mediated by ligands such as activin and myostatin, thereby inhibiting downstream Smad2/3 phosphorylation. In experimental research, it serves as a critical tool for modulating muscle mass and metabolic homeostasis to investigate muscle atrophy, osteoporosis, and cancer-associated cachexia.