Others Antibody
LGN-523 (AML-01, IGN523) is a humanized monoclonal antibody targeting the human CD98 heavy chain (SLC3A2) . Overexpressed in various tumors, particularly acute myeloid leukemia (AML), CD98 is involved in amino acid transport and integrin signaling. This antibody exerts anti-tumor activity by mediating potent ADCC, complement-dependent cytotoxicity (CDC), and inducing lysosomal membrane permeabilization.
Product Specifications
Target
Others
Clonality
Monoclonal
Conjugation
Unconjugated
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
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