IFNAR Antibody
Anti-IFNAR1 Antibody (Anifrolumab) is a humanized IgG1 kappa monoclonal antibody targeting the type I interferon receptor subunit 1 (IFNAR1) . This product specifically binds to IFNAR1, blocking the interaction of all type I interferons (including all subtypes of IFN-alpha, IFN-beta, and IFN-omega) with the receptor complex. This inhibition blocks the activation of the downstream JAK/STAT signaling pathway, reduces the expression of interferon-stimulated genes (ISGs), and suppresses type I interferon-mediated immune responses.
Product Specifications
Target
IFNAR
Clonality
Monoclonal
Conjugation
Unconjugated
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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