CCR Antibody
R707 is a humanized monoclonal antibody expressed in CHO cells targeting C-C chemokine receptor type 7 (CCR7/CD197) . R707 specifically binds to CCR7, blocking its interaction with ligands CCL19 and CCL21. This blockade inhibits CCR7-mediated cell migration, chemotaxis, and lymphocyte homing to lymph nodes. It exhibits significant biological activity in researching chronic lymphocytic leukemia (CLL), autoimmune diseases, and lymph node metastasis of tumor cells.
Product Specifications
Target
CCR
Clonality
Monoclonal
Conjugation
Unconjugated
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
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