SJ000291942

SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway. BMPs are members of the transforming growth factor beta (TGFβ) family of secreted signaling molecules.

Product Specifications

CAS Number

[425613-09-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

TGF-β Receptor

Type

Reference compound

Related Pathways

TGF-beta/Smad

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/SJ000291942.html

Purity

99.66

Solubility

DMSO : ≥ 150 mg/mL

Smiles

O=C(NC1=CC=C(F)C([N+]([O-])=O)=C1)COC2=CC=C(CC)C=C2

Molecular Formula

C16H15FN2O4

Molecular Weight

318.30

Precautions

H302, H315, H319, H335

References & Citations

[1]Genthe JR, et al. Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway. ACS Chem Biol. 2017 Sep 15;12 (9) :2436-2447.