Tempone-H

Tempone-H may be used as a spin trap in chemical and biological systems to quantify peroxynitrite and superoxide radical formation. Ferric and cupric ions are effective oxidants of Tempone-H[1][2].

Product Specifications

CAS Number

[3637-11-4]

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tempone-h.html

Concentration

10mM

Purity

99.08

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1CC(C)(C)N(O)C(C)(C)C1

Molecular Formula

C9H17NO2

Molecular Weight

171.24

References & Citations

[1]Dikalov S, et al. Quantification of peroxynitrite, superoxide, and peroxyl radicals by a new spin trap hydroxylamine 1-hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine. Biochem Biophys Res Commun. 1997 Jan 3;230 (1) :54-7.|[2]Dikalov SI, et al. Amyloid beta peptides do not form peptide-derived free radicals spontaneously, but can enhance metal-catalyzed oxidation of hydroxylamines to nitroxides. J Biol Chem. 1999 Apr 2;274 (14) :9392-9.