(Rac) -TTA-P2
(Rac) -TTA-P2 is the isomer of TTA-P2 (HY-10035), and can be used as an experimental control. TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of T-Type calcium channel. TTA-P2 penetrates well the CNS and blocks the native T-type currents in deep cerebellar nuclear neurons, the window current is completely abolished both for wild-type and mutant Cav3.1 channels. TTA-P2 has the potential for the research of neurology disease[1].
Product Specifications
CAS Number
[918430-49-6]
Product Name Alternative
(Rac) -T-Type calcium channel inhibitor
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Calcium Channel; Drug Isomer
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rac-tta-p2.html
Purity
98.69
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(NCC1(F)CCN(CC2CC(OCC2)(C)C)CC1)C3=CC(Cl)=CC(Cl)=C3
Molecular Formula
C21H29Cl2FN2O2
Molecular Weight
431.37
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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