3-Epiursolic Acid
3-Epiursolic Acid is a triterpenoid that can be isolated from Eriobotrya japonica, acts as a competitive inhibitor of cathepsin L (IC50, 6.5 μM; Ki, 19.5 μM), with no obvious effect on cathepsin B[1].
Product Specifications
CAS Number
[989-30-0]
UNSPSC
12352211
Hazard Statement
H303, H371
Target
Cathepsin
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-epiursolic-acid.html
Purity
99.77
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC([C@]12[C@]([C@H]([C@H](C)CC2)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)([C@H](O)CC4)C)([H])CC5)C)([H])[C@]5(C)[C@]3(C)CC1)=O
Molecular Formula
C30H48O3
Molecular Weight
456.70
Precautions
H303, H371
References & Citations
[1]3-Epiursolic Acid, et al. Triterpenoids as novel natural inhibitors of human cathepsin L. Chem Biodivers. 2014 Sep;11 (9) :1354-63.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Cathepsin B; Cathepsin K; Cathepsin L
Available Sizes
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