Cytosporone B
Cytosporone B (Csn-B; Dothiorelone G) is a naturally occurring nuclear orphan receptor Nur77/NR4A1 agonist with an EC50 of 0.278 nM.
Product Specifications
CAS Number
[321661-62-5]
Product Name Alternative
Csn-B; Dothiorelone G
UNSPSC
12352005
Hazard Statement
H302
Target
Nuclear Hormone Receptor 4A/NR4A
Type
Natural Products
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Cytosporone_B.html
Purity
99.23
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : ≥ 50 mg/mL
Smiles
O=C(OCC)CC1=CC(O)=CC(O)=C1C(CCCCCCC)=O
Molecular Formula
C18H26O5
Molecular Weight
322.40
Precautions
H302
References & Citations
[1]Zhan Y, et al. Cytosporone B is an agonist for nuclear orphan receptor Nur77. Nat Chem Biol. 2008 Sep;4 (9) :548-56.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Nur77/NR4A1
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