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Cytosporone B

Cytosporone B (Csn-B; Dothiorelone G) is a naturally occurring nuclear orphan receptor Nur77/NR4A1 agonist with an EC50 of 0.278 nM.

Product Specifications

CAS Number

[321661-62-5]

Product Name Alternative

Csn-B; Dothiorelone G

UNSPSC

12352005

Hazard Statement

H302

Target

Nuclear Hormone Receptor 4A/NR4A

Type

Natural Products

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Cytosporone_B.html

Purity

99.23

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : ≥ 50 mg/mL

Smiles

O=C(OCC)CC1=CC(O)=CC(O)=C1C(CCCCCCC)=O

Molecular Formula

C18H26O5

Molecular Weight

322.40

Precautions

H302

References & Citations

[1]Zhan Y, et al. Cytosporone B is an agonist for nuclear orphan receptor Nur77. Nat Chem Biol. 2008 Sep;4 (9) :548-56.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Nur77/NR4A1

Available Sizes

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