CDK9-IN-8
CDK9-IN-8 is a highly effective and selective CDK9 inhibitor with an IC50 of 12 nM.
Product Specifications
CAS Number
[2105956-51-0]
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/CDK9-IN-8.html
Purity
99.16
Solubility
DMSO : 5.2 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
FC1=CC=C(NC(C2(CC2)C(NC3=CC=C(NC4=NC=C5C(N(C6CCCC6)C(C(N(C)C)=O)=C5)=N4)C=C3)=O)=O)C=C1
Molecular Formula
C31H32FN7O3
Molecular Weight
569.63
References & Citations
[1]Li Y, et al. Discovery of a highly potent, selective and novel CDK9 inhibitor as an anticancer drug candidate. Bioorg Med Chem Lett. 2017 Aug 1;27 (15) :3231-3237.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK9
Available Sizes
Curated Selection
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