URAT1&XO inhibitor 3
URAT1&XO inhibitor 3 (compound 27) is an orally active anti-gout agent targeting XO (IC50: 35 nM) and URAT1 (IC50: 31 nM) . URAT1&XO inhibitor 3 has good pharmacological and pharmacokinetic (PK) characteristics and in vivo safety[1].
Product Specifications
CAS Number
2089040-93-5
UNSPSC
12352005
Target
URAT1
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/urat1-xo-inhibitor-3.html
Smiles
O=C(O)C1=CC=C(C2=C(OC(F)=C3)C3=CC(C#N)=C2)C=C1O
Molecular Formula
C16H8FNO4
Molecular Weight
297.24
References & Citations
[1]Discovery of a Potent and Orally Bioavailable Xanthine Oxidase/Urate Transporter 1 Dual Inhibitor as a Potential Treatment for Hyperuricemia and Gout
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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