Sipoglitazar
Sipoglitazar is an orally active agonist of PPAR. Sipoglitazar can be used to study diabetes[1].
Product Specifications
CAS Number
[342026-92-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/sipoglitazar.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCC1=CN(CC2=CC=C(OCC3=CSC(C4=CC=CC=C4)=N3)C=C2)N=C1OCC
Molecular Formula
C25H25N3O4S
Molecular Weight
463.55
Precautions
P261-P280-P302+P352
References & Citations
[1]Nishihara M, et al. An unusual metabolic pathway of sipoglitazar, a novel antidiabetic agent: cytochrome P450-catalyzed oxidation of sipoglitazar acyl glucuronide. Drug Metab Dispos. 2012 Feb;40 (2) :249-58.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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