Sipoglitazar

Sipoglitazar is an orally active agonist of PPAR. Sipoglitazar can be used to study diabetes[1].

Product Specifications

CAS Number

[342026-92-0]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/sipoglitazar.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CCC1=CN(CC2=CC=C(OCC3=CSC(C4=CC=CC=C4)=N3)C=C2)N=C1OCC

Molecular Formula

C25H25N3O4S

Molecular Weight

463.55

Precautions

P261-P280-P302+P352

References & Citations

[1]Nishihara M, et al. An unusual metabolic pathway of sipoglitazar, a novel antidiabetic agent: cytochrome P450-catalyzed oxidation of sipoglitazar acyl glucuronide. Drug Metab Dispos. 2012 Feb;40 (2) :249-58.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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