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ANR94

ANR94 is a potent and selective adenosine A2A receptor (AA2AR) antagonist with an Ki of 46 nM for hAA2AR. ANR94 has the potential for the research of Parkinson's disease[1][2].

Product Specifications

CAS Number

634924-89-3

UNSPSC

12352005

Hazard Statement

H301

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/anr94.html

Concentration

10mM

Purity

98.91

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

NC1=C2N=C(OCC)N(CC)C2=NC=N1

Molecular Formula

C9H13N5O

Molecular Weight

207.23

Precautions

H301

References & Citations

[1]Volpini R, et al. Adenosine A2A receptor antagonists: new 8-substituted 9-ethyladenines as tools for in vivo rat models of Parkinson's disease. ChemMedChem. 2009;4 (6) :1010-1019. |[2]Micioni Di Bonaventura MV, et al. Regulation of adenosine A2A receptor gene expression in a model of binge eating in the amygdaloid complex of female rats. J Psychopharmacol. 2019;33 (12) :1550-1561.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Adenosine A2A receptor (A2AR)

Available Sizes

Frequently Asked Questions

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