IL Receptor Antibody

Anti-IL-5 Antibody (e.g., Mepolizumab) is a humanized monoclonal antibody that specifically neutralizes interleukin-5 (IL-5), effectively disrupting the signaling for eosinophil activation and survival by blocking the ligand-receptor interaction. In allergic inflammation models, this antibody significantly diminishes tissue eosinophil infiltration and alleviates airway hyperresponsiveness.