TLR Antibody

Anti-TLR7 Antibody is a humanized monoclonal antibody targeting Toll-like receptor 7 (TLR7) . TLR7 is a pattern recognition receptor primarily located on endosomal membranes that recognizes single-stranded RNA (ssRNA), playing a pivotal role in antiviral immune responses and autoimmune diseases such as Systemic Lupus Erythematosus (SLE) . This antibody specifically binds to TLR7, blocking its activation by ligands (e.g., viral RNA or synthetic agonists) and subsequently inhibiting the downstream MyD88-dependent signaling pathway and the production of Type I interferons (IFN-α/β) . By modulating TLR7 signaling, Anti-TLR7 Antibody serves as a valuable tool for investigating viral infection mechanisms and therapeutic strategies for autoimmune disorders.