IGF-I R, Human (HEK293, His, solution)
IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, His, solution) is the recombinant human-derived IGF-I R protein, expressed by HEK293 , with C-His labeled tag.
Product Specifications
Product Name Alternative
IGF-I R Protein, Human (HEK293, His, solution), Human, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/igf-i-r-protein-human-932a-a-hek293-his.html
Purity
95.0
Smiles
Molecular Formula
3480 (Gene_ID) P08069 (E31-N932) (Accession)
Molecular Weight
Approximately 150&120&48 kDa
Shipping Conditions
Dry ice
Storage Conditions
Stored at -80°C for 1 year
Scientific Category
Recombinant Proteins
Available Sizes
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RBPJ, NT (RBPJ, IGKJRB, IGKJRB1, RBPJK, RBPSUH, Recombining binding protein suppressor of hairless, CBF-1, J kappa-recombination signal-binding protein, RBP-J kappa, Renal carcinoma antigen NY-REN-30) (MaxLight 650)