Human BMP-14 Protein, His tag (Animal-Free)
Bone Morphogenetic Protein-14 (BMP-14), known as Growth differentiation factor 5 (GDF5), is an extracellular multifunctional cytokine that is also a member of the TGFβ family. BMP-14 can bind with the TGFβ receptor and trigger SMAD protein signal transduction. BMP-14 plays a role in skeletal and joint development and increases the survival of neurons that respond to the neurotransmitter dopamine.
Product Specifications
Background
Product Name Alternative
Bone morphogenetic protein 14, Cartilage-Derived Morphogenetic Protein-1, Growth/Differentiation Factor-5, GDF-5, CDMP-1, BMP14
Gene ID
8200
Accession Number
P43026
Tag
BMP-14
Type
Cytokines and proteins
Applications
His tag
Purity
> 98 % as determined by SDS-PAGE
Activity
Measure by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED₅₀ for this effect is <14 ng/mL.
Molecular Formula
14.52 kDa
Molecular Weight
14.52 kDa
Precautions
Features & Benefits
Endotoxin :< 0.1 EU per 1 μg of the protein as determined by the LAL method.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Protein Length
The recombinant Human BMP-14 consists of 121amino acids and predicts a molecular mass of 14.52 kDa.
Formulation
Lyophilized from sterile 20mM sodium citrate,0.2 M NaCl, pH 3.5.
Applications Notes
Human
Other Product Names
BMP14, BMP-14, BMP 14, bone morphogenetic protein 14, Cartilage-Derived Morphogenetic Protein-1, Growth/Differentiation Factor-5, GDF-5, CDMP-1
Recommended Usage
Preparation
E.coli
Accession Number URL
https://www.uniprot.org/uniprotkb/P43026/entry
AA Sequence
Amino acid sequence derived from Human BMP-14 (Met381-Arg501) (P43026) was expressed with 6xHis tag at the C-terminus.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
TYRP1 (Tyrosinase Related Protein 1) (TA99), CF640R conjugate, 0.1mg/mL
HLA-Aw32 & HLA-A25 (MHC I) (CATA-1), CF640R conjugate, 0.1mg/mL
Von Willebrand Factor (3E2D10), CF405S conjugate, 0.1mg/mL
CD59 (heavy chain of Protectin) (BRA-10G), CF488A conjugate, 0.1mg/mL
