2'-OMe-A (Bz) Phosphoramidite
2'-OMe-A (Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis[1].
Product Specifications
CAS Number
110782-31-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/2-ome-a-bz-phosphoramidite.html
Purity
99.74
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=CC=C(C(C2=CC=C(OC)C=C2)(OC[C@@H]3[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OC)[C@H](N4C(N=CN=C5NC(C6=CC=CC=C6)=O)=C5N=C4)O3)C7=CC=CC=C7)C=C1
Molecular Formula
C48H54N7O8P
Molecular Weight
887.96
Precautions
H302, H315, H319, H335
References & Citations
[1]Honcharenko D, et al. 2'-O- (N- (Aminoethyl) carbamoyl) methyl Modification Allows for Lower Phosphorothioate Content in Splice-Switching Oligonucleotides with Retained Activity. Nucleic Acid Ther. 2022 Jun;32 (3) :221-233.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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