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2'-Deoxyguanosine (Standard)

Product Specifications

UNSPSC Description

2'-Deoxyguanosine (Standard) is the analytical standard of 2'-Deoxyguanosine. This product is intended for research and analytical applications. 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells[1][2][3]. In Vitro: 2'-Deoxyguanosine inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively[1].

Target Antigen

Endogenous Metabolite

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-deoxyguanosine-standard.html

Smiles

OC[C@@H](O[C@H](C1)N2C3=C(N=C2)C(NC(N)=N3)=O)[C@H]1O

Molecular Weight

267.24

References & Citations

[1]Ross DD, et al. Effects of deoxynucleosides on cultured human leukemia cell growth and deoxynucleotide pools. Cancer Res. 1981 Nov;41(11 Pt 1):4493-8.|[2]Kizaki H, et al. Adenosine, deoxyadenosine, and deoxyguanosine induce DNA cleavage in mouse thymocytes. J Immunol. 1988 Sep 1;141(5):1652-7.|[3]Brulfert A, et al. Deoxyguanosine, a potent cytokinesis inhibitor in plant cells. Experientia. 1974 Sep 15;30(9):1010-1.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-17563R/2-Deoxyguanosine-Standard-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-17563R/

CAS Number

961-07-9

Available Sizes

Curated Selection

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