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Budipine (hydrochloride)

Budipine hydrochloride is an anti-parkinson agent. Budipine hydrochloride also is a substrate of P-glycoprotein (P-gp), is mediated the uptake into the brain by P-gp. Budipine hydrochloride also is N-methyl-d-aspartate (NMDA) antagonist, and has indirect dopaminergic effects through an improved dopamine release, the inhibition of monoamine oxidase type B (MAO-B) . Budipine hydrochloride can be used for the research of CNS disorders include Parkinson disease[1].

Product Specifications

CAS Number

63661-61-0

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/budipine-hydrochloride.html

Smiles

CC(N1CCC(C2=CC=CC=C2)(C3=CC=CC=C3)CC1)(C)C.[H]Cl

Molecular Formula

C21H28ClN

Molecular Weight

329.91

References & Citations

[1]Manfred Uhr, et al. The anti-Parkinson drug budipine is exported actively out of the brain by P-glycoprotein in mice. Neurosci Lett. 2005 Jul 22-29;383 (1-2) :73-6.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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