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Amyloid Precursor Protein (APP), Peptide #3, #4, #5 Antibody

Three different affinity-purified anti-peptide antibodies were combined to make this product. The concentrations of each of the three antibodies was 100 μg/mL (based on absorbance at 280nm), making the total antibody concentration 300 μg/mL. The antibody preparation is at a concentration of 100 μg/mL (based on absorbance at 280 nm) . The presence of antibodies against three different regions of APP increases IHC sensitivity and fluorescence intensity.

Product Specifications

Product Name Alternative

Amyloid-beta A4 protein (ABPP) (APPI) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta precursor protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha) ; Soluble APP-beta (S-APP-beta) ; C99 (Beta-secretase C-terminal fragment) (Beta-CTF) ; Amyloid-beta protein 42 (Abeta42) (Beta-APP42) ; Amyloid-beta protein 40 (Abeta40) (Beta-APP40) ; C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF) ; P3 (42) ; P3 (40) ; C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID (59) ) (Gamma-CTF (59) ) ; Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID (57) ) (Gamma-CTF (57) ) ; Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID (50) ) (Gamma-CTF (50) ) ; C31]

UniProt

P05067

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptides (QHF QEK VES LEQ EAA NER AA {residues #433-452}, EQK DRQ HTL KHF EHV RMV DPK K {residues #501-522}, EEI QDE VDE LLQ KEQ NYS DD, residues #556-575}) from the human APP gene product

Target

Amyloid Precursor Protein (APP), Peptide #3, #4, #5

Clonality

Polyclonal

Conjugation

Unconjugated

Purification

Affinity-Purified IgY

Concentration

300 μg/mL

Dilution

IHC: 1:500-1:1000; ICC: 1:500-1:1000

Form

Liquid

Molecular Weight

87 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

ICC, IHC

Host or Source

Gallus

Preservative

Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (“PBS, " pH 7.2) with sodium azide (0.02%, w/v) added as a preservative.

Isotype

IgY

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