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(D-Tyr5, D-Ser (tBu) 6, Azagly10) -LHRH

Selected Variant

HY-P4577

Size: 1 Each

(D-Tyr5, D-Ser (tBu) 6, Azagly10) -LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH) . LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) [1].

Product Specifications

CAS Number

1426173-74-1

UNSPSC

12352209

Target

GnRH Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/d-tyr5-d-ser-tbu-6-azagly10-lhrh.html

Solubility

H2O

Smiles

O=C([C@@H]1CCC(N1)=O)N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@@H](CO)C(N[C@@H](C(N[C@H](COC(C)(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N3[C@@H](CCC3)C(NNC(N)=O)=O)=O)=O)=O)=O)CC4=CC=C(C=C4)O)=O)=O)CC5=CNC6=CC=CC=C56)=O

Molecular Formula

C59H84N18O14

Molecular Weight

1269.41

References & Citations

[1]Horvath JE, et al. Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats. Proc Natl Acad Sci U S A. 2002 Nov 12;99 (23) :15048-53.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

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