ELN484228
ELN484228 is a blocker of α-synuclein which is a key protein in Parkinson’s disease.
Product Specifications
CAS Number
[312-63-0]
UNSPSC
12352005
Hazard Statement
H302, H319
Target
α-synuclein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ELN484228.html
Purity
99.50
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=S(C1=CC=CC=C1)(NC2=CC=C(F)C=C2)=O
Molecular Formula
C12H10FNO2S
Molecular Weight
251.28
Precautions
H302, H319
References & Citations
[1]Tóth G, et al. Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease. PLoS One. 2014 Feb 14;9 (2) :e87133.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α-synuclein
Available Sizes
Curated Selection
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