IHMT-MST1-58
IHMT-MST1-58 is a potent, selective mammalian and orally active STE20-like protein 1 kinase (MST1) inhibitor with IC50 value of 23 nM. IHMT-MST1-58 can be used for the research of Type 1/2 diabetes[1].
Product Specifications
CAS Number
2414484-25-4
UNSPSC
12352005
Target
Hippo (MST)
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ihmt-mst1-58.html
Purity
99.05
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=S(C1=CC=C(NC(N=C2N(C)C3C4=CC=CC=C4C)=NC=C2N(C)C3=O)C=C1)(N)=O
Molecular Formula
C21H22N6O3S
Molecular Weight
438.50
References & Citations
[1]Yun Wu, et al. Discovery of IHMT-MST1-58 as a Novel, Potent, and Selective MST1 Inhibitor for the Treatment of Type 1/2 Diabetes. J Med Chem. 2022 Sep 8;65 (17) :11818-11839
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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