Myristic acid

Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties[1][2][3][4].

Product Specifications

CAS Number

[544-63-8]

UNSPSC

12352211

Hazard Statement

H319

Target

Bacterial; Endogenous Metabolite; NF-κB

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; NF-κB

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Myristic_acid.html

Purity

99.88

Solubility

DMSO : 200 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)

Smiles

CCCCCCCCCCCCCC(O)=O

Molecular Formula

C14H28O2

Molecular Weight

228.37

Precautions

H319

References & Citations

[1]Hu M, et al. Myristic acid regulates triglyceride production in bovine mammary epithelial cells through the ubiquitination pathway. Agriculture, 2023, 13 (10) : 1870.|[2]Oepen K, et al. Myristic Acid Inhibits the Activity of the Bacterial ABC Transporter BmrA. Int J Mol Sci. 2021 Dec 17;22 (24) :13565.|[3]Alonso-Castro AJ, et al. Myristic acid reduces skin inflammation and nociception. J Food Biochem. 2022 Jan;46 (1) :e14013.|[4]Huang Q, et al. Anti-inflammatory effects of myristic acid mediated by the NF-κB pathway in lipopolysaccharide-induced BV-2 microglial cells. Mol Omics. 2023 Oct 30;19 (9) :726-734.