PABPC1 Antibody (Center)
Rabbit polyclonal antibody to PABPC1 (Polyadenylate-binding protein 1) is a cytoplasmic-nuclear shuttling protein important for protein translation initiation, and both RNA processing and stability. PABPC1 binds the poly (A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing.
Product Specifications
Product Name Alternative
Anti-Polyadenylate-binding protein 1 antibody, anti-Poly (A) -binding protein 1 antibody, anti-PABP 1 antibody, anti-PABPC2 antibody, anti-PABP1 antibody, anti-PAB1 antibody, anti-PABPC1 antibody
UniProt
P11940
Reactivity
Human, Mouse
Immunogen
Synthetic Peptide
Target
PABPC1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Infectious Disease & Virology, Molecular Biology
Dilution
WB - 1:1000, IHC-P - 1:50-100
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Molecular Weight
70671
References & Citations
Peng, Yuanzheng et al. Cytoplasmic poly (A) -binding protein 1 (PABPC1) interacts with the RNA-binding protein hnRNPLL and thereby regulates immunoglobulin secretion in plasma cells J Biol Chem, 292, 12285-12295 (2017)
Pubmed id
28611064
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Prediction Reactivity
Other, Rat
Tested Applications
IHC-P, WB
NCBI Accession Number
NP_002559.2
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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