RICTOR Antibody (C-term)
Rabbit polyclonal antibody to RICTOR (Rapamycin insensitive companion of mTOR antibody) is also known as AVO3, PIA. It belongs to the pianissimo family. The Rictor-FRAP complex plays a role in PKC alpha phosphorylation, directly phosphorylates Akt/PKB on Ser473 in vitro and facilitates Thr308 phosphorylation by PDK1and it has also function as a drug target in tumors that have lost expression of PTEN, a tumor suppressor that opposes activation of Akt/PKB.
Product Specifications
Product Name Alternative
Anti-KIAA1999 antibody
UniProt
Q6R327
Reactivity
Human, Mouse
Immunogen
Synthetic Peptide
Target
RICTOR
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology, Signal Transduction
Dilution
WB - 1:1000, IHC-P - 1:10-50
Form
Molecular Weight
192218
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Tested Applications
IHC-P, WB
NCBI Accession Number
NP_689969.2
Host or Source
Rabbit
Isotype
Rabbit IgG
Frequently Asked Questions
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