Isaxonine

Isaxonine acts as a modifier of the surface pH of the bilayer[1]. Isaxonine accelerates the rate of peripheral nerve regeneration, stimulate axonal sprouting and promote motor and sensory function recovery[2]. Isaxonine is a neurotrophic agent[3].

Product Specifications

CAS Number

[4214-72-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/isaxonine.html

Purity

99.54

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)NC1=NC=CC=N1

Molecular Formula

C7H11N3

Molecular Weight

137.18

Precautions

H302, H315, H319, H335

References & Citations

[1]De Bleecker J, et al. Influence of isaxonine on the target phenomenon, muscle fibre size and neuromuscular junction in the tenotomized and denervated gastrocnemius muscle of the rat. Acta Neuropathol. 1986;69 (3-4) :337-340. |[2]J De Bleecker, et al. Influence of Isaxonine on the target phenomenon, muscle fibre size and neuromuscular junction in the tenotomized and denervated gastrocnemius muscle of the rat. Acta Neuropathol. 1986;69 (3-4) :337-40.|[3]C M Becker, et al. Nerve and muscle regeneration after axonal division in rats treated with Isaxonine phosphate (isopropylamino-2-pyrimidine phosphate) . Eur Surg Res. 1986;18 (6) :383-9.|[4]J De Reuck, et al. Influence of Isaxonine on reinnervation of the rat gastrocnemius muscle. Acta Neuropathol. 1987;72 (4) :406-8.|[5]A Davy, et al. [Hepatotoxicity of Isaxonine phosphate: 4 cases of severe subacute hepatitis]. Gastroenterol Clin Biol. 1984 Oct;8 (10) :715-9.