9-Fluorenol

9-Fluorenol (9-Hydroxyfluorene; compound 3) is a dopamine (DAT) inhibitor with IC50 value of 9 μM. 9-Fluorenol is a major metabolite of compound developed as a wake promoting agent. 9-Fluorenol shows wake promotion activity in vivo[1].

Product Specifications

CAS Number

[1689-64-1]

Product Name Alternative

9-Hydroxyfluorene

UNSPSC

12352005

Hazard Statement

H302

Target

Dopamine Receptor; Drug Metabolite

Type

Reference compound

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/9-fluorenol.html

Purity

99.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1C2=CC=CC=C2C3=CC=CC=C31

Molecular Formula

C13H10O

Molecular Weight

182.22

Precautions

H302

References & Citations

[1]Dunn D, et al. Wake promoting agents: search for next generation modafinil, lessons learned: part III. Bioorg Med Chem Lett. 2012 Jun 1;22 (11) :3751-3.